作者：Shrilekha Vedhakrishnan（1）;玛丽亚·维纳斯（1）;皮拉尔·卡萨多·莫雷诺（Pilar Casado Moreno）（1）;克拉拉·本尼迪·加西亚（Clara Benedi-Garcia）（1）;Carlos Dorronsoro（1）;苏珊娜·马科斯（1）
（1）马德里，马德里，马德里，西班牙
Date:2020年6月
Source:Arvo 2020摘要 - 视频演示
Summary
Influence of centre near (CN) design multifocal lenses (1-day Acuvue Moist) on visual acuity was measured in young adults and presbyopes under cyclopegic and natural conditions with the effect of different pupil sizes modelled using an adaptive optics system. Overall the lenses performed similarly at improving near VA between cyclopleged young adults and presbyopes when compared to no lenses, and created no apparent difference to near VA in accommodating young adults, however there was slight degradation to distance VA.
临床relevance
中心近设计多灶性镜头，当适合年轻人时，还可以增加+2.50的功率，似乎不会降低敏锐度，但是与没有多焦点透镜的条件相比，距离似乎有轻微的VA降解。
局限性和未来研究
- Meeting abstract so not fully peer-reviewed
- Statistics are not included in the abstract and no error bars are displayed on the presented charts to hep infer significance of findings - consequently outcomes can only be considered as observational.
- Young adults examined so can only infer if the same outcomes would be found in children.
- Outcomes from centre distance designs would be interesting to know for comparison.
Full story
首席作者在她的视频演示中解释说，中心距离设计多灶性CL被提议通过诱导外围散热器来减慢MP，而靠近设计的中心因诱导负球形异常而弥补了适应性滞后。
在这项研究中，使用自适应光学系统，在两组具有和没有的参与者的参与者中，研究了附近（CN）设计多灶性CL（1天刺激：BVP -2.00D：+1.25，+1.75，+2.50）周围的（未披露的周期性杂志程度）。
小组：
- 年轻的近视（n = 10）26.9±2.2yr；-4.50d
- 长老会（n = 5）53±2年；-2.75d
主要调查：
- 比较了视觉降解或远距离与MCL相比，这两组
- 通过年轻近视和长老会之间的焦点表现，视觉中的恒定
- CN多灶性CL’的住宿在视觉性能中的作用
Sessions:
- Paralysed accommodation; pupil sizes 3, 4, 5mm
- Natural accommodation and pupil size
措施：
- Through focus VA, tumbling E, alternative forced choice
自适应光学： - Badal system to induce and correct defocus
- Charts displayed on CRT monitor
- 使用人工学生控制的学生大小
结论
所有三个多病灶的添加改善VA在公关的附近esbyopes and in cyclopleged young adults as expected, however the results revealed an apparent slight decrease to distance VA across all subjects when compared to without multifocal lenses. The +1.25D add lens showed similar behaviour to the no lens condition, with depth of focus increasing for the +1.75D and +2.25D adds with increasing pupil sizes. The main outcome of interest when considering centre near multifocal designs for myopia control in children is that VA is maintained across all distances with active accommodation. However, there was considerable inter subject variation in responses described by the authors as likely being due to differences in interaction between unique individual optical aberrations profiles and the optical aberration profiles provided by the lenses.
抽象的
标题：Vision with multifocal contact lens in myopes and presbyopes
目的：在同时视觉原理下工作的多灶性隐形眼镜（MCL）是老花贝的已知解决方案，但还建议它们控制近视的进展。我们使用中心设计MCL在长老会和近视管中的中心设计MCL进行了视觉性能，以进行不同的距离，观看条件和瞳孔直径。
方法：Measurements were performed in a group of 10 myopic subjects (MS, age: 24-27; SE: ±to-4.5D) and 5 presbyopes (PS, age: 47-58; SE:-2.75-+2.5D) on an Adaptive Optics system. All subjects were fitted with MCLs (three adds: LA: +1.25D; MA: +1.75D; HA: +2.5D), all with the same distance power (-2D). Residual defocus was corrected by a Badal System (BS). Decimal Visual Acuity (VA) was measured using an 8- Alternative Forced Choice procedure, tumbling E letter displayed on a CRT monitor (Visage, Cambridge research system), at different vergences (Far: 0D, Intermediate: +1.75D, Near: +2.50D). Measurements were performed both for paralyzed accommodation (PA, 5, 4 & 3 mm pupil), and natural accommodation (NA, natural pupil). Eye without the lens (NL) was measured as a control. The DOF was estimated as the dioptric range for which VA is 0.5 or better. The effect of the lens, addition, pupil diameter and accommodation was analyzed in the 2 study populations.
Results:在NA下，MCLS的VA范围为1.13-1.07（MS）和远处0.95-0.8（PS），近1.13-1.07（MS）和0.5-0.45（PS）的近距离，下降了1.18/1.09（1.18/1.09（MS/PS）对于LA，MA为1.24/1.29（MS/PS），而HA的HA为1.22/1.21（MS/PS）。在PA下，对于5mm瞳孔，平均VA值比MS中的NA值低1.32倍，而PS的平均值低1.05倍。Na和Pa（7/5mm瞳孔）下TFVA曲线之间的平均RMS差为0.23/0.04（MS/PS，NL），0.21/0.03（MS/PS，LA），0.17/0.06（MS/PS，MA，MA）），0.13/0.03（MS/PS，HA）。DOF范围从-3d/-2.5d（NL）到YS（Na/Pa）的1D/1D（ha），从-2d/-1.5d（nl）到1D/1D/1D（Na/pa）（na/pa））。
结论：MCL在Young受试者和长老会中降低了VA，同时增加了DOF（在两组中瘫痪的适应下，以及老花腰上的自然条件）。两种效果与透镜添加的大小成正比。在容纳年轻受试者时，MCL似乎并没有差距差异，并且将其保留为诺伦斯州。
About Paul
Dr Paul Giffordis a research scientist and industry innovator based in Brisbane, Australia, and co-founder of Myopia Profile.
